• br Conclusions In the current study we found that the

  2024-02-21

  

  Conclusions In the current study, we found that the exposure of maduramicin to chicken myocardial HAT Inhibitor II results in cellular damage and even death via the induction of apoptosis. Maduramicin upregulated the expression of apoptotic genes and activated caspase cascades, which were accompa

• br The role of apelin in hepatic diseases

  2024-02-21

  

  The role of apelin in hepatic diseases The involvement of the apelin/APJ system in liver physiology and pathology has been proven in numerous studies (Table 6). For instance, in the experiment of Emam et al. [63] on rats suffering from hepatic injury, apelin decreased the levels of ALT, AST and L

• br HMG proteins mobile modulators of

  2024-02-21

  

  HMG proteins: mobile modulators of chromatin structure and cellular phenotype The term “High Mobility Group” was originally coined for the HMG proteins because of their unusual solubility properties, their small size and their rapid mobility, relative to other chromatin proteins, during gel elect

• br Technical Note Fungal spoilage of

  2024-02-21

  

  Technical Note Fungal spoilage of dairy products remains a major concern for dairy manufacturers despite the use of preventive and control approaches, including the use of chemical preservatives. Among methods that are increasingly used by industries for microbial contaminant control, biopreserva

• Our conclusion was confirmed by two experiments The

  2024-02-20

  

  Our conclusion was confirmed by two experiments. The addition of aminopeptidase-specific inhibitors at high concentrations allowed us to exclude the possibility of substrate hydrolysis by other proteases present in the samples, for example, endoproteases. After the application of inhibitors, we were

• The application of diuretics induce an increased rate of wat

  2024-02-20

  

  The application of diuretics induce an increased rate of water exiting brain cells encouraging the formation of increased intracellular polyphosphoric acid. In the absence of the diuretic water is retained in cells converting polyphosphoric CP 154526 to monophosphoric acid. The latter change decrea

• Recent genome wide association studies have

  2024-02-20

  

  Recent genome-wide association studies have indicated SORL1 as a risk factor for AD (Meng et al., 2007, Rogaeva et al., 2007, Wen et al., 2013). SORL1, is expressed in neurons (Yin et al., 2015) and also regulates APP traffic from the cell membrane to the Golgi apparatus. A reduction in its expressi

• In the QFP rs T allele showed

  2024-02-20

  

  In the QFP, rs2269657-T allele showed a significant correlation with reduced plaque density in frontal cortices (Table 2), strengthening the association with amyloid pathology. The same MLN 9708 region was shown to exhibit a statistically significant reduction of SREBF2 mRNA levels in rs2269657-T ca

• Introduction Inflammasomes are large cytosolic protein compl

  2024-02-20

  

  Introduction Inflammasomes are large cytosolic protein complexes with multiple components that trigger a rapid immune response against pathogen-associated molecular pattern WAY 316606 (PAMPs) during pathogen infections or damage-associated molecular pattern molecules (DAMPs) during tissue damage [1

• Since the first studies of betaine aldehyde oxidation in

  2024-02-20

  

  Since the first studies of betaine aldehyde oxidation in rats [13], the participation of betaine in the detoxification of homocysteine has well described, considering the activity of other leukotriene receptor antagonists as betaine homocysteine methyltransferase and methionine synthase. But, there

• Nrf br AhR br Nrf and AhR friends

  2024-02-20

  

  Nrf2 AhR Nrf2 and AhR: friends or foes for energetic metabolism? Perspectives in carcinogenesis upon xenobiotic exposure Acknowledgements Introduction Integration of endogenous and exogenous signals via appropriate receptors is at the core of biological differentiation and adaptive r

• br Adenosine receptors and the

  2024-02-20

  

  Adenosine receptors and the adaptive immunity T lymphocytes are responsible for the cell-mediated immune response [95]. These cells can be stimulated by the presentation of antigenic moieties by APCs, such as dendritic cells or macrophages [96]. The presentation of antigenic molecules on the APC

• Introduction Myasthenia gravis MG is an autoimmune disorder

  2024-02-20

  

  Introduction Myasthenia gravis (MG) is an autoimmune disorder characterized by muscle weakness, which is mainly due to autoantibodies reducing the number or function of postsynaptic 3-Deazaadenosine receptors (AChRs) [1], [2]. Animal models have been developed to uncover the immunopathogenesis of

• br Conflict of interest statement br Benign prostatic hyperp

  2024-02-20

  

  Conflict of interest statement Benign prostatic hyperplasia (BPH) is a highly complex process characterized by an increased number of epithelial and stromal CCT251545 in the transition zone. , , Autopsy studies by McNeal detail the evolution of histological changes within these 2 cellular compa

• br Dihydrotestosterone in adult fish and frogs br New perspe

  2024-02-20

  

  Dihydrotestosterone in adult fish and frogs New perspectives and next directions Similar to other androgens, DHT can modulate reproductive endpoints in both fish and amphibians. However, predicting the effects of DHT can be challenging, as reproductive homeostasis is dependent upon the balance

16488 records 205/1100 page Previous Next First page 上5页 201202203204205 下5页 Last page