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The finding that MHC and myogenin expression does not change
2018-11-08
The finding that MHC and myogenin expression does not change upon ectopic Msx1 expression but decreases drastically upon Msx2 expression is another piece of evidence for the selective role of MSX2 in dedifferentiation. The previous two studies on MSX1 induction in myotubes did not characterize MHC l
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Immunohistochemical studies revealed increase in the proport
2018-11-08
Immunohistochemical studies revealed increase in the proportion of CD44highCD24low cell type from low in normal tissues to quite high in tumours. This is interesting as we know that Cancer Stem Cells are the actual tumour initiating subpopulation and can expand depending on its evolutionary landscap
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Recent reports have indicated the functional significance
2018-11-08
Recent reports have indicated the functional significance of FOXM1 in pluripotent cells. FOXM1 is required for the maintenance of pluripotency in mouse embryonal carcinoma (EC) cells, via direct regulation of Oct4 transcription (Xie et al., 2010). More importantly, FOXM1 is important for maintaining
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br Author disclosure statement br Acknowledgements Authors
2018-11-08
Author disclosure statement Acknowledgements Authors would like to thank Dr. T. Ramakrishna Murti for his valuable comments and linguistic corrections in the manuscript. Authors would also like to thank D.I Biotech (Seoul, Korea) for support to analyze neurite outgrowth. This work was support
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Next to the significant evidence that CpG
2018-11-08
Next to the significant evidence that CpG methylation of the HLA-G promoter is important for the transcriptional activity of the gene (Moreau et al., 2003; Mouillot et al., 2005), HLA-G Amyloid Beta-peptide (25-35) is also post-transcriptionally regulated by the 3′UTR. Several polymorphic sites in
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We have found a rare population
2018-11-08
We have found a rare population of pNSCs in the adult mammalian brain (termed AdpNSCs). We isolated cells from the adult periventricular region that generate clonally derived, self-renewing, and multipotent colonies in vitro in the presence of LIF. These LIF colonies can be passaged to give rise to
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A striking finding from this work is that in
2018-11-08
A striking finding from this work is that, in serum-free conditions, chicken PGCs can survive and proliferate in the absence of stem cell factor (SCF). SCF (c-KIT ligand) is a requisite survival factor for mouse PGCs at early embryonic stages and for survival in short-term culture experiments (Gu et
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In the present study we show that
2018-11-08
In the present study, we show that rhLNs are more effective in supporting xeno-free and defined differentiation compared with exogenous matrix such as gelatin, used in ongoing clinical studies (Schwartz et al., 2012). Moreover, we demonstrate that suspension transplantations of rhLN-521-hESC-RPE int
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br Results and Discussion br Experimental Procedures br
2018-11-08
Results and Discussion Experimental Procedures Author Contributions Acknowledgments We would like to thank Hospital de São João for bone marrow samples and buffy coats. This work had the financial support of FCT/MEC through National Funds and, when applicable, co-financed by the FEDER th
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Third we use a conceptually relevant measure to
2018-11-07
Third, we use a conceptually relevant measure to understand links between skin tone and health. Many prior studies have relied on a handheld narrow-band reflectance meter designed and validated for measuring skin pigmentation in a person\'s inner arm (e.g., Borrell, Kiefe, Williams, Diez-Roux, & Gor
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The current essay has its limitations More systematic review
2018-11-07
The current essay has its limitations. More systematic reviews on religion and health exist elsewhere (Hummer et al., 2004; Koenig, 2009; Marks, 2005; McCullough et al., 2000; Seeman et al., 2003). Rather than doing a review that would involve empirical assessments of a set of literature, we have so
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br Results Table shows descriptive statistics for the
2018-11-07
Results Table 1 shows descriptive statistics for the full sample. A small percentage (3%) of Malawian children was born premaritally whereas the vast majority of children (69.7%) were born to mothers who married before their birth. There is further diversity in mothers’ marital status: approximat
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auda The discount rate is the degree
2018-11-07
The discount rate is the degree to which a subject reduces the current value of a future reward. Usually, the research measures this rate with choice models by inviting subjects to choose real or hypothetical amounts of money in different time periods (Frederick, Loewenstein, & O’Donoghue, 2002). O
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br Balanza petrolera Como muestra el cuadro el valor
2018-11-07
Balanza petrolera Como muestra el cuadro 1, el valor de las exportaciones de Pemex alcanzó su tope en 2011, cuando se colocaron en el exterior casi 60 000 millones de dólares de crudo y petrolíferos (las de petroquímicos han sido marginales). Todavía en 2014, de acuerdo con cifras preliminares, d
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br The use of a
2018-11-07
The use of a legacy telephone system, often called plain old telephone system (POTS), or any variety of mobile phone in healthcare, is neither new nor novel. Since the beginning of telephony in the late 19th century, the phone has been a great tool to physicians (). Physicians, or their clinic off
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